Wales have been forced into five changes to the starting XV that beat Ireland last week for the trip to Scotland on Saturday, a 4.45pm kick-off at Murrayfield.
This is due to there being seven new injuries in Wayne Pivac’s squad this week, joining Jon Davies (injury) and Josh Adams (COVID breach) as unavailable for selection, as the depths of the player pool in Wales is tested.
The tight five remains unchanged but Aaron Wainwright starts on the blindside after Dan Lydiate was released from the squad with a torn ACL, Josh Navidi picked up a short-term neck injury and Josh MacLeod ruptured his achilles and will likely be released from the squad next week.
There is a new face at scrum-half as Gareth Davies replaces Tomos Williams who limped off with a hamstring injury against Ireland, while Nick Tompkins and Owen Watkin form a new centre partnership after Johnny Williams (concussion) and George North (foot) were ruled out.
The final change comes on the wing where Hallam Amos (concussion) is also unavailable and Liam Williams returns after serving his ban.
On the bench James Botham will provide back row cover, Kieran Hardy steps in as the scrum-half option and Willis Halaholo could make his Wales debut if called upon in the outside backs.
Wales: Leigh Halfpenny, Liam Williams, Owen Watkin, Nick Tompkins, Louis Rees-Zammit, Dan Biggar, Gareth Davies; Wyn Jones, Ken Owens, Tomas Francis, Adam Beard, Alun Wyn Jones (c), Aaron Wainwright, Justin Tipuric, Taulupe Faletau
Replacements: Elliot Dee, Rhodri Jones, Leon Brown, Will Rowlands, James Botham, Kieran Hardy, Callum Sheedy, Willis Halaholo