There are 13 changes to the Wales side to face Georgia on Saturday as Wayne Pivac shakes things up in a bid to put an end to the six-game losing streak the team are currently on.
The side includes three debutants in the starting XV as James Bothan, Kieran Hardy and Johnny Williams win their first caps, while Callum Sheedy will make his full debut after coming off the bench against Ireland last week.
Up front there is a completely new front five as Wyn Jones, Elliot Dee and Samson Lee pack down in the front row, while Seb Davies and Jake Ball form the second row partnership. Justin Tipuric is the only survivor in the back row and captains the side as Botham is named on the blindside and Aaron Wainwright gets the nod at number eight.
Hardy, Sheedy and Williams are the new 9, 10 and 12 combo in the backs, with Nick Tompkins recalled to start at outside. Liam Williams is the other survivor, switching from wing to full-back, allowing Louis Rees-Zammit to make his full debut on one wing with Johnny McNicholl coming in on the other.
There is a potential debutant on the bench too where Ioan Lloyd will cover fly-half and full-back, with Rhys Webb and Jonah Holmes the other backs options. Sam Parry, Nicky Smith and Leon Brown are the replacement front row, while Cory Hill covers second row and James Davies is the back row option.
Wales: Liam Williams, Johnny McNicholl, Nick Tompkins, Johnny Williams, Louis Rees-Zammit, Callum Sheedy, Kieran Hardy; Wyn Jones, Elliot Dee, Samson Lee, Jake Ball, Seb Davies, James Botham, Justin Tipuric, Aaron Wainwright
Replacements: Sam Parry, Nicky Smith, Leon Brown, Cory Hill, James Davies, Rhys Webb, Ioan Lloyd, Jonah Holmes